HYALURONIDASE

Staphylococcal hyaluronidase.

Hyaluronidase and peribulbar block.

We have assessed the effect of two concentrations of hyaluronidase on the quality of peribulbar block, using a low volume, single injection technique. We studied 200 patients undergoing elective intraocular surgery, allocated randomly to one of three groups. Group 1 (n = 50) received peribulbar block with 5 ml of a 1:1 mixture of 0.5% plain bupivacaine and 2% plain lignocaine. Group 2 (n = 75) ...

Hyaluronidase in Ophthalmology

ABSTRACT Purpose The application of hyaluronidase in ophthalmology dates back 60 years, when it was first included in retrobulbar blocks. Now it is used routinely in retrobulbar, peribulbar, and sub-Tenon’s blocks. Until recently, the only sources of hyaluronidase were animal derived, either pharmaceutically manufactured or compounded. Animal-derived products have been associated with low purit...

Introduction Plasma Hyaluronidase (Hyal-1) Genomic Organization of the Hyaluronidase Sequences Hyaluronidase Genes on Chromosome 3p21.3 Hyaluronidase Genes on Chromosome 7q31.3 Implications for Clinical Medicine Hyaluronidases in Cancer

he has focused on the biology of hyaluronan and the hyaluronidases. He is also a board-certified Anatomic Pathologist and participates in the teaching and diagnostic services of the Department of Pathology. He is currently a visiting scientist in the laboratory of Dr. Robert Stern in San Francisco. In addition to hyaluronan and hyaluronidase, his interests include the process of aging and the b...

Hyaluronidase from Tadpole Tissue.

The connective tissues of the tadpole undergo extensive remodeling during metamorphosis. In the resorbing tail fins of bullfrog tadpoles, there is a rapid degradation of collagen in the basement lamella coupled with dehydration and loss of the gelatinous core of the fin (1,2). The layers of the dense collagenous basement lamella are loosened, frayed, and invaded by mesenchymal cells.1 A collage...